Case file · CIK 0001009258

Deerfield Management Company, L.P.

Healthcare and biotech specialist capital sample.

Deerfield Management Company, L.P.Firm profile
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Q4 2025 · SEC 13F case file

Deerfield Management Company, L.P.

13F value$7.8BTop themeMixedTop 1052.3%Lines150
#1NUVLOther22.2%
#2BROOKDALE SR LIVING INCOther5.5%
#3COGTOther4.1%
#4PRAXOther3.4%
#5CNCOther3.4%

KOL-style case note

This is the public 13F money map for Deerfield Management Company, L.P..

Healthcare and biotech specialist capital sample. This page turns the latest public filing into a shareable research story: what the entity owns, which theme is driving the portfolio, and where to investigate next.

Who this is

Healthcare and biotech specialist capital sample. It belongs in a smart-money radar because its public 13F shows quarterly capital direction and theme preference.

Top holding

The latest filing's largest public position is NUVL, around 22.2% of the disclosed 13F portfolio. That is the first place to look for the current thesis.

Main theme

Mixed is the clearest public theme in the portfolio. The important question is whether that theme repeats across the top positions, not just whether one stock worked.

Portfolio shape

The latest public portfolio is about $7.8B, with 150 lines and roughly 52.3% in the top 10. Higher concentration means a few decisions can explain more of the proxy return.

Why track it

This is not a live trading signal. It is a quarterly capital map: start with the ranking, inspect the top holdings, then ask whether the manager has a repeatable framework.

How to read it

13F filings are delayed and incomplete. They do not show shorts, many derivatives, private positions, cash, or current trade timing. Use this page to generate research questions, not to replace diligence.

Smart Money VelocityVelocity score blends 13F value growth, concentration, theme purity, option exposure, and filing history. It is a prioritization score, not a return.

53
Velocity + theme concentration

Score blends filing growth, concentration, theme purity, call exposure, and filing history.

13F value

$7.8BQ4 2025, latest public filing

Growth since first filing

1.75x$4.5B$7.8B

Reporting lag13F filings arrive after the quarter ends. The page shows a delayed public snapshot, not live positions.

45dQuarter-end snapshot, not live positions
Public Disclosure Proxy Return

This is not actual fund performance. Returns and rankings use public disclosures after they become visible, not private NAV or live trading.

Disclosure workflow

How to read this page

Every number is anchored to a public quarterly filing. The report date is the portfolio snapshot; the filing date is when the market could actually see it.

Report quarterQ4 2025Public filing date2026-02-17Ranking startsafter public filingRanking gate70% price coverageCoverage is the share of eligible public holdings that can be mapped to a ticker and priced. Debt, internal funds, and non-priced lines are excluded from the denominator.

Public holdings

Q4 2025 exposure map

15013F lines
HoldingThemeTypeValue%
NUVALENT INCNUVL · 17,248,450 sharesOtherSH$1.7B22.2%
BROOKDALE SR LIVING INC112463AF1 · 306,885,000 sharesOtherPRN$427.5M5.5%
COGENT BIOSCIENCES INCCOGT · 9,043,903 sharesOtherSH$321.2M4.1%
PRAXIS PRECISION MEDICINES IPRAX · 903,351 sharesOtherSH$266.3M3.4%
CENTENE CORP DELCNC · 6,447,998 sharesOtherSH$265.3M3.4%
VIATRIS INCVTRS · 20,206,170 sharesOtherSH$251.6M3.2%
REVOLUTION MEDICINES INCRVMD · 2,894,613 sharesOtherSH$230.6M2.9%
UNITED THERAPEUTICS CORP DELUTHR · 425,993 sharesOtherSH$207.6M2.7%
VERA THERAPEUTICS INCVERA · 4,059,695 sharesOtherSH$205.6M2.6%
MIRUM PHARMACEUTICALS INC604749AB7 · 70,000,000 sharesSemisPRN$180.7M2.3%
CELCUITY INCCELC · 1,714,000 sharesOtherSH$171M2.2%
NEUROCRINE BIOSCIENCES INCNBIX · 1,184,345 sharesOtherSH$168M2.1%
IONIS PHARMACEUTICALS INCIONS · 1,979,669 sharesSemisSH$156.6M2.0%
NEWAMSTERDAM PHARMA COMPANYNAMS · 4,164,789 sharesSemisSH$146.1M1.9%
INSPIRE MED SYS INC457730109 · 1,505,872 sharesOtherSH$138.9M1.8%
LEGEND BIOTECH CORPLEGN · 5,932,000 sharesOtherSH$129M1.6%
BROOKDALE SR LIVING INC112463104 · 11,637,032 sharesOtherSH$125.6M1.6%
INDIVIOR PLCINDV · 3,393,063 sharesOtherSH$121.7M1.6%
ARROWHEAD PHARMACEUTICALS INARWR · 1,832,946 sharesSemisSH$121.7M1.6%
LARIMAR THERAPEUTICS INCLRMR · 30,606,974 sharesOtherSH$116.6M1.5%
CATALYST PHARMACEUTICALS INCCPRX · 4,911,161 sharesSemisSH$114.6M1.5%
ADAPTHEALTH CORPAHCO · 11,477,730 sharesOtherSH$114.3M1.5%
BIOCRYST PHARMACEUTICALS INCBCRX · 14,341,000 sharesSemisSH$111.9M1.4%
IONIS PHARMACEUTICALS INC462222AF7 · 60,000,000 sharesSemisPRN$95.3M1.2%
ALIGNMENT HEALTHCARE INC01625VAB0 · 61,000,000 sharesOtherPRN$92.6M1.2%
ARS PHARMACEUTICALS INCSPRY · 7,503,812 sharesSemisSH$87.4M1.1%
PHARVARIS N VPHVS · 3,126,042 sharesOtherSH$86.7M1.1%
SAVARA INCSVRA · 13,569,000 sharesOtherSH$81.8M1.0%
IDEAYA BIOSCIENCES INCIDYA · 2,153,043 sharesOtherSH$74.4M0.95%
CERTARA INCCERT · 7,808,605 sharesOtherSH$68.8M0.88%
BIO RAD LABS INC090572207 · 226,070 sharesOtherSH$68.5M0.87%
NEOGENOMICS INC64049MAB6 · 72,689,000 sharesOtherPRN$64.7M0.83%
ACADIA HEALTHCARE COMPANY INACHC · 4,520,000 sharesOtherSH$64.1M0.82%
BRIDGEBIO ONCOLOGY THERAPEUTBBOT · 4,885,446 sharesOtherSH$61.2M0.78%
STOKE THERAPEUTICS INCSTOK · 1,823,500 sharesOtherSH$57.9M0.74%
LANTHEUS HLDGS INCLNTH · 827,999 sharesOtherSH$55.1M0.70%
STRUCTURE THERAPEUTICS INCGPCR · 767,993 sharesOtherSH$53.4M0.68%
ENVISTA HOLDINGS CORPORATIONNVST · 2,280,498 sharesOtherSH$49.5M0.63%
ENHABIT INCEHAB · 4,747,746 sharesOtherSH$43.8M0.56%
KYMERA THERAPEUTICS INCKYMR · 561,170 sharesOtherSH$43.7M0.56%
CAREDX INCCDNA · 2,191,000 sharesOtherSH$41.3M0.53%
DISC MEDICINE INCIRON · 511,163 sharesOtherSH$40.6M0.52%
SIONNA THERAPEUTICS INCSION · 970,590 sharesOtherSH$39.9M0.51%
LIVANOVA PLC53802LAB8 · 34,280,000 sharesOtherPRN$39.7M0.51%
BELITE BIO INCBLTE · 233,813 sharesOtherSH$37.4M0.48%
DAY ONE BIOPHARMACEUTICALS I23954D109 · 3,723,131 sharesSemisSH$34.7M0.44%
PHREESIA INCPHR · 1,999,045 sharesOtherSH$33.8M0.43%
EMBECTA CORPEMBC · 2,752,031 sharesOtherSH$32.7M0.42%
VERACYTE INCVCYT · 726,000 sharesOtherSH$30.6M0.39%
MODERNA INCMRNA · 1,000,000 underlying sharesHedgePUT$29.5M0.38%
LANTHEUS HLDGS INC516544AB9 · 25,255,000 sharesOtherPRN$28.9M0.37%
BETA BIONICS INCBBNX · 938,308 sharesOtherSH$28.6M0.37%
VENTAS INCVTR · 354,000 sharesOtherSH$27.4M0.35%
IMMUNOCORE HLDGS PLC45258DAB1 · 30,000,000 sharesOtherPRN$27.1M0.35%
ALNYLAM PHARMACEUTICALS INCALNY · 67,935 sharesSemisSH$27M0.35%
TANGO THERAPEUTICS INCTNGX · 2,906,946 sharesOtherSH$25.8M0.33%
XENON PHARMACEUTICALS INCXENE · 542,020 sharesSemisSH$24.3M0.31%
SPYRE THERAPEUTICS INCSYRE · 710,626 sharesOtherSH$23.3M0.30%
FOGHORN THERAPEUTICS INCFHTX · 3,649,211 sharesOtherSH$19.7M0.25%
COMPASS THERAPEUTICS INCCMPX · 3,606,000 sharesOtherSH$19.4M0.25%
EDGEWISE THERAPEUTICS INCEWTX · 765,694 sharesOtherSH$19M0.24%
KYVERNA THERAPEUTICS INCKYTX · 2,000,000 sharesOtherSH$18.8M0.24%
TAYSHA GENE THERAPIES INCTSHA · 2,722,165 sharesOtherSH$15M0.19%
CORMEDIX INCCRMD · 1,107,944 sharesOtherSH$12.9M0.16%
THE ONCOLOGY INSTITUTE INCTOI · 3,360,052 sharesOtherSH$12M0.15%
MONOPAR THERAPEUTICS INCMNPR · 170,558 sharesOtherSH$11.1M0.14%
MEDLINE INCMDLN · 260,000 sharesOtherSH$10.9M0.14%
OMADA HEALTH INCOMDA · 553,107 sharesOtherSH$8.7M0.11%
CALCIMEDICA INCCALC · 1,300,000 sharesOtherSH$8.6M0.11%
PRESTIGE CONSMR HEALTHCARE I74112D101 · 69,669 sharesOtherSH$4.3M0.05%
CULLINAN THERAPEUTICS INCCGEM · 386,169 sharesOtherSH$4M0.05%
VEEVA SYS INCVEEV · 17,711 sharesOtherSH$4M0.05%
RADNET INCRDNT · 49,951 sharesOtherSH$3.6M0.05%
LABCORP HOLDINGS INCLH · 13,825 sharesOtherSH$3.5M0.04%
ENOVIS CORPORATIONENOV · 127,270 sharesOtherSH$3.4M0.04%
ALIGNMENT HEALTHCARE INCALHC · 164,345 sharesOtherSH$3.2M0.04%
QUEST DIAGNOSTICS INCDGX · 18,392 sharesOtherSH$3.2M0.04%
TRANSMEDICS GROUP INCTMDX · 25,492 sharesOtherSH$3.1M0.04%
INSULET CORPPODD · 10,616 sharesOtherSH$3M0.04%
ANNEXON INCANNX · 583,913 sharesOtherSH$2.9M0.04%
BIOLIFE SOLUTIONS INCBLFS · 120,211 sharesOtherSH$2.9M0.04%
CHEMED CORP NEWCHE · 6,215 sharesOtherSH$2.7M0.03%
PETCO HEALTH & WELLNESS CO IWOOF · 936,309 sharesOtherSH$2.6M0.03%
ORTHOPEDIATRICS CORPKIDS · 144,220 sharesOtherSH$2.6M0.03%
THE CIGNA GROUPCI · 9,203 sharesOtherSH$2.5M0.03%
TRUPANION INCTRUP · 66,438 sharesOtherSH$2.5M0.03%
RESMED INCRMD · 10,104 sharesOtherSH$2.4M0.03%
BOSTON SCIENTIFIC CORPBSX · 24,941 sharesOtherSH$2.4M0.03%
DAVITA INCDVA · 20,909 sharesOtherSH$2.4M0.03%
DOXIMITY INCDOCS · 51,942 sharesOtherSH$2.3M0.03%
DEXCOM INCDXCM · 32,943 sharesOtherSH$2.2M0.03%
IRHYTHM TECHNOLOGIES INCIRTC · 12,099 sharesOtherSH$2.1M0.03%
NEWAMSTERDAM PHARMA COMPANYNAMS · 92,787 sharesSemisSH$2.1M0.03%
CONMED CORPCNMD · 52,555 sharesOtherSH$2.1M0.03%
MASIMO CORPMASI · 16,147 sharesOtherSH$2.1M0.03%
LEMAITRE VASCULAR INCLMAT · 25,815 sharesOtherSH$2.1M0.03%
10X GENOMICS INCTXG · 126,574 sharesOtherSH$2.1M0.03%
ATRICURE INCATRC · 52,076 sharesOtherSH$2.1M0.03%
AVANOS MED INCAVNS · 167,061 sharesOtherSH$1.9M0.02%
CORVEL CORPCRVL · 27,629 sharesOtherSH$1.9M0.02%
CARDINAL HEALTH INCCAH · 8,985 sharesOtherSH$1.8M0.02%
GOODRX HLDGS INCGDRX · 660,133 sharesOtherSH$1.8M0.02%
SURGERY PARTNERS INCSGRY · 112,623 sharesOtherSH$1.7M0.02%
ALIGN TECHNOLOGY INCALGN · 11,000 sharesOtherSH$1.7M0.02%
ADDUS HOMECARE CORPADUS · 15,871 sharesOtherSH$1.7M0.02%
MERIT MED SYS INC589889104 · 18,798 sharesOtherSH$1.7M0.02%
NATIONAL HEALTHCARE CORPNHC · 12,085 sharesOtherSH$1.7M0.02%
ALECTOR INCALEC · 1,055,192 sharesOtherSH$1.6M0.02%
ENCOMPASS HEALTH CORPEHC · 15,259 sharesOtherSH$1.6M0.02%
VAREX IMAGING CORPVREX · 131,745 sharesOtherSH$1.5M0.02%
HEALTHEQUITY INCHQY · 16,231 sharesOtherSH$1.5M0.02%
ABBOTT LABSABT · 11,449 sharesOtherSH$1.4M0.02%
MAXIMUS INCMMS · 16,606 sharesOtherSH$1.4M0.02%
STRYKER CORPORATIONSYK · 3,551 sharesOtherSH$1.2M0.02%
ALPHATEC HLDGS INCATEC · 57,277 sharesOtherSH$1.2M0.02%
STAAR SURGICAL COSTAA · 51,894 sharesOtherSH$1.2M0.02%
EDWARDS LIFESCIENCES CORPEW · 13,702 sharesOtherSH$1.2M0.01%
UFP TECHNOLOGIES INCUFPT · 5,098 sharesOtherSH$1.1M0.01%
KENVUE INCKVUE · 65,344 sharesOtherSH$1.1M0.01%
MIMEDX GROUP INCMDXG · 160,419 sharesOtherSH$1.1M0.01%
INTEGER HLDGS CORPITGR · 13,326 sharesOtherSH$1M0.01%
REVVITY INCRVTY · 10,323 sharesOtherSH$998.8K0.01%
AZENTA INCAZTA · 25,835 sharesOtherSH$859.3K0.01%
ARVINAS INCARVN · 68,057 sharesOtherSH$807.2K0.01%
ZOETIS INCZTS · 5,698 sharesOtherSH$716.9K0.01%
COOPER COS INC216648501 · 7,786 sharesOtherSH$638.1K0.01%
SCHRODINGER INCSDGR · 33,987 sharesOtherSH$607.7K0.01%
TANDEM DIABETES CARE INCTNDM · 26,090 sharesOtherSH$573.5K0.01%
RXSIGHT INCRXST · 52,257 sharesOtherSH$544.5K0.01%
INTEGRA LIFESCIENCES HLDGS CIART · 39,209 sharesOtherSH$487K0.01%
ABBVIE INCABBV · 2,014 sharesOtherSH$460.2K0.01%
HARROW INCHROW · 8,693 sharesOtherSH$426K0.01%
XERIS BIOPHARMA HOLDINGS INCXERS · 52,230 sharesSemisSH$410K0.01%
HEALTHCARE SVCS GROUP INC421906108 · 21,259 sharesOtherSH$406.5K0.01%
AMPHASTAR PHARMACEUTICALS INAMPH · 14,852 sharesSemisSH$397.7K0.01%
REPLIGEN CORPRGEN · 2,199 sharesOtherSH$360.3K0.00%
STERIS PLCSTE · 1,352 sharesOtherSH$342.8K0.00%
BELLRING BRANDS INCBRBR · 11,996 sharesOtherSH$320.7K0.00%
INTUITIVE SURGICAL INCISRG · 483 sharesOtherSH$273.6K0.00%
NATIONAL VISION HLDGS INCEYE · 10,284 sharesOtherSH$265.5K0.00%
BIOMX INCPHGE · 131,270 sharesOtherSH$245.5K0.00%
HUMANA INCHUM · 917 sharesOtherSH$234.9K0.00%
ABEONA THERAPEUTICS INCABEO · 40,000 sharesOtherSH$210.8K0.00%
THE ONCOLOGY INSTITUTE INCTOI · 1,250,000 sharesOtherSH$150.6K0.00%
QUANTUM SI INCQSI · 333,333 sharesOtherSH$66.8K0.00%
NUVATION BIO INCNUVB · 166,666 sharesOtherSH$55K0.00%
BUTTERFLY NETWORK INCBFLY · 733,333 sharesOtherSH$12.9K0.00%
PMV PHARMACEUTICALS INCPMVP · 8,790 sharesSemisSH$11K0.00%
SURROZEN INCSRZN · 166,666 sharesOtherSH$3.3K0.00%
MYRIAD GENETICS INCMYGN · 505 sharesOtherSH$3.1K0.00%

Quarter tape

Reported 13F value

SEC EDGAR
Q1 2023$4.5BQ2 2023$4.7BQ3 2023$4.5BQ4 2023$5.4BQ1 2024$5.7BQ2 2024$6BQ3 2024$6.7BQ4 2024$5.3BQ1 2025$5.1BQ2 2025$5.5BQ3 2025$6.6BQ4 2025$7.8B

Signal breakdown

Why this matters

53
VelocityVelocity score blends 13F value growth, concentration, theme purity, option exposure, and filing history. It is a prioritization score, not a return.

13F value is 1.75x the first tracked filing.

52
ConcentrationPurity describes how much of the portfolio is concentrated in one inferred theme. It is useful when a manager is expressing a very specific thesis.

Top ten public lines are 52.3% of the latest report.

99
Holdings

150 reportable lines in the latest public filing.

12
History

12 tracked quarterly 13F reports in the database or seed layer.

Publisher mode

Twitter-ready card

Evidence layer

What is public, what is inferred

Public SEC data

13F reports disclose long reportable U.S. securities and long put/call options. They do not show cash, private stakes, shorts, written options, or current live holdings.

Inferred theme

Theme tags are deterministic product analysis from issuer, CUSIP, option type, and keyword rules. They are not SEC labels.

Daily automation

Vercel Cron calls the EDGAR ingestion endpoint every day and records per-manager ingestion results.